Guest Host: Steve Roberts

A new study suggests antidepressants may be no more effective than placebo in all but severe cases of depression. A look at how drug effectiveness is measured and weighed against safety concerns in and beyond the drug approval process.


  • Dr. William Potter serves on the FDA's Psychopharmacologic Drugs Advisory Committee, vice president for translational neuroscience at Merck Research Laboratories; board-certified psychiatrist
  • Dr. Jerry Avorn Professor of Medicine at Harvard Medical School; Chief of the Division of Pharmacoepidemiology and Pharmacoeconomics at Brigham and Women's Hospital; author "Powerful Medicines: The Benefits, Risks, and Costs of Prescription Drugs"
  • Blair Johnson professor of psychology, University of Connecticut; coauthor on new antidepressant study
  • Gardiner Harris science reporter for "The New York Times"

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